Ipamorelin

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Ipamorelin lyophilised research peptide in Australia, supplied for in-vitro laboratory investigation. Synthetic pentapeptide selective agonist of the ghrelin / growth-hormone-secretagogue receptor GHS-R1a (sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂). ≥99% purity by HPLC, third-party Certificate of Analysis available. Dispatched within 1-3 business days. Research use only. Not for human consumption, therapeutic use, or diagnostic application.

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Product details

Research Context

Ipamorelin is a synthetic pentapeptide and a selective small-molecule agonist of the growth-hormone secretagogue receptor (GHS-R1a), the same receptor that endogenous ghrelin acts on. It belongs to the broader class of growth-hormone-releasing peptides (GHRPs) and is structurally unrelated to growth hormone releasing hormone (GHRH). The molecule incorporates three non-standard amino acids (Aib, D-2-Nal, D-Phe) that confer receptor selectivity and resistance to enzymatic degradation. It is supplied as a lyophilised white powder for laboratory investigation.

This material is supplied strictly for in-vitro laboratory investigation. Preclinical studies in the published literature have examined Ipamorelin in the context of pituitary cell-culture growth-hormone secretion assays, ghrelin receptor binding studies, and comparative pharmacology of growth-hormone secretagogues. No therapeutic, prophylactic, or diagnostic application is claimed or implied, and the peptide is not approved for human or veterinary use in Australia.

Chemistry & Structural Modification

Ipamorelin is a 5-residue C-terminally amidated peptide with sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂, where Aib is 2-aminoisobutyric acid, D-2-Nal is D-2-naphthylalanine, and D-Phe is D-phenylalanine. The three non-standard residues are central to its selectivity at GHS-R1a.

  • Molecular formula: C38H49N9O5
  • Molecular weight: 711.9 g/mol
  • CAS number: 170851-70-4; PubChem CID 20754357

Lyophilisation & Stability

Supplied as a sterile-filtered, lyophilised white powder under inert gas in a sealed vial. The freeze-dried form is the standard preservation state for research peptides of this molecular class and supports extended shelf life when stored as directed below.

Storage

Store lyophilised vial at 2 to 8°C, protected from light. (Long-term storage at −20°C is standard practice.)

Reconstituted solution: 2 to 8°C, used within 14 to 30 days. Avoid repeated freeze-thaw cycles.

Quality & Documentation

  • Purity: ≥99% by HPLC
  • Certificate of Analysis (COA): published on our COA page.