GHK-Cu
Price range: $50.00 through $80.00
Processing time is 1–2 business days.
GHK-Cu lyophilised research peptide in Australia, supplied for in-vitro laboratory investigation. Naturally occurring tripeptide-copper complex (Gly-His-Lys coordinated with Cu²⁺), the form most commonly used in dermal cell-culture research. ≥99% purity by HPLC, third-party Certificate of Analysis available. Dispatched within 1-3 business days. Research use only. Not for human consumption, therapeutic use, or diagnostic application.
Research Context
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK), a naturally occurring sequence derived from human plasma albumin. The free GHK tripeptide has a strong affinity for divalent copper and forms a stable square-pyramidal coordination complex in solution. GHK-Cu is supplied as a lyophilised powder with the characteristic blue colour of copper-peptide complexes and is the form of GHK most commonly used in skin-biology and cell-culture research literature.
This material is supplied strictly for in-vitro laboratory investigation. Preclinical studies in the published literature have examined GHK-Cu in the context of fibroblast culture, gene-expression profiling, collagen-related enzyme activity assays, and dermal extracellular-matrix models. No therapeutic, prophylactic, or diagnostic application is claimed or implied.
Chemistry & Structural Modification
The peptide backbone has sequence Gly-His-Lys (one-letter GHK) and is a 3-residue tripeptide. The copper(II) ion is coordinated by the glycine amino terminus, the deprotonated glycine to histidine peptide-bond nitrogen, and the histidine imidazole nitrogen, giving the complex its characteristic colour and stability.
- Molecular formula (Cu complex): C14H24CuN6O4 (protonated form; the deprotonated form C14H22CuN6O4 is also reported in the literature)
- Molecular weight: approximately 403.9 g/mol (protonated complex)
- PubChem CID: 378611 (Cu-GHK complex)
Lyophilisation & Stability
Supplied as a sterile-filtered, lyophilised blue powder under inert gas in a sealed vial. The freeze-dried form is the standard preservation state for copper-peptide complexes of this molecular class and supports extended shelf life when stored as directed below.
Storage
Store lyophilised vial at 2 to 8°C, protected from light. (Long-term storage at −20°C is standard practice.)
Reconstituted solution: 2 to 8°C, used within 14 to 30 days. Avoid repeated freeze-thaw cycles.
Quality & Documentation
- Purity: ≥99% by HPLC
- Certificate of Analysis (COA): published on our COA page.
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