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Retatrutide

Retatrutide

Price range: $110.00 through $240.00

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Retatrutide lyophilised research peptide in Australia, supplied for in-vitro laboratory investigation. Synthetic 39-residue lipidated polypeptide investigated as a triple agonist at the GLP-1, GIP, and glucagon receptors in preclinical metabolic research. ≥99% purity by HPLC, third-party Certificate of Analysis available. Dispatched within 1-3 business days. Research use only. Not for human consumption, therapeutic use, or diagnostic application.

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Product details

Research Context

Retatrutide is a synthetic, lipidated polypeptide and is an investigational triple agonist acting at the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon (GCGR) receptors. Structurally it is built on a modified GIP backbone with non-coded residues (aminoisobutyric acid, α-methylleucine) and a fatty-acid conjugate on a central lysine, which together extend its plasma half-life and reduce proteolytic degradation in laboratory assay systems.

This lyophilised material is supplied exclusively for in-vitro laboratory and scientific investigation. Preclinical studies have examined receptor binding profiles, second-messenger signalling at GLP-1R, GIPR, and GCGR, and metabolic-pathway readouts in cultured cells and rodent tissue. No therapeutic, performance, or human-use claims are made or implied.

Chemistry & Structural Modification

Retatrutide is a long-chain polypeptide bearing a non-natural α-methylleucine residue, two aminoisobutyric acid residues, and a polyethylene-glycol-linked γ-glutamyl-eicosanedioic-acid side chain conjugated to a central lysine. The lipid conjugate is the principal driver of albumin binding in plasma-stability assays.

  • Molecular formula: C221H342N46O68
  • Molecular weight: 4731.33 g/mol
  • CAS number: 2381089-83-2

Lyophilisation & Stability

Each vial is supplied as a sterile lyophilised solid. Lyophilisation removes bulk water while preserving the lipidated peptide in a low-moisture, non-reactive matrix, which is critical for compounds bearing long-chain fatty-acid conjugates that are susceptible to hydrolysis in aqueous solution. Sealed vials remain stable for extended periods when stored cold and protected from light and moisture.

Storage

Store lyophilised vial at 2 to 8°C, protected from light. (Long-term storage at −20°C is standard practice.)

Reconstituted solution: 2 to 8°C, used within 14 to 30 days. Avoid repeated freeze-thaw cycles.

Quality & Documentation

  • Purity: ≥99% by HPLC
  • Certificate of Analysis (COA): published on our COA page.

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